Cetrimonium Chloride and Bromide, and Steartrimonium Chloride, carry a positive charge that attracts them to the slightly negatively charged skin and hair proteins, accounting for their use as antistatics. It can be used with non-ionic and cationic surfactants and most polar solvents. Cetrimonium Chloride is a a light hair conditioning agent. Description. Cetrimonium Chloride. These ingredients may be used as preservatives at a maximum concentration of 0.1%. Cetrimonium Chloride and Cetrimonium Bromide also help to cleanse the skin or to prevent odor by destroying or inhibiting the growth of microorganisms and by helping water to mix with oil and dirt so that they can be rinsed away. Cetrimonium Bromide and Cetrimonium Chloride are quaternary am-. Physical hazards. All Rights Reserved. Learn more | Legal Disclaimer, Beyond providing Skin Deep as an educational tool for consumers, EWG offers its EWG VERIFIED mark as a quick and easily identifiable way of conveying personal care products that meet EWG's strict health criteria. PRODUCT AND COMPANY IDENTIFICATION Product Name: Cetyltrimethylammonium Bromide (CTAB) Synonyms/Generic Names: Cetrimonium bromide; N,N,N-trimethyl-1-hexadecanaminium bromide; Hexadecyltrimethylammonium bromide; Palmityltrimethylammonium bromide; CTAB INCI Name: Cetrimonium chloride, water Bioderma Sensibio H2O Micellar Water ingredients explained: Aqua/Water/Eau, Peg-6 Caprylic/Capric Glycerides, Fructooligosaccharides, Mannitol, Xylitol, Rhamnose, Cucumis Sativus (Cucumber) Fruit Extract, Propylene Glycol, Cetrimonium Bromide, Disodium Edta In cosmetics and personal care products, these ingredients are used in the formulation of hair conditioners, hair dyes and colors, other hair care products, and in some skin care products. H373 May cause damage to organs (Gastrointestinal tract) through prolonged or repeated exposure if swallowed. What is CETRIMONIUM BROMIDE and where is it found? A synergistic blend of geranium, palmarosa, orange and corn mint essential oils help to soothe and clarify the skin while calming the senses. Its uses include providing a buffer solution for the extraction of DNA. Description. Privacy Policy | Cosmeticsinfo.org, The Science & Safety Behind Your Favorite Products. Cetrimonium Chloride and Bromide, and Steartrimonium Chloride, carry a positive charge that attracts them to the slightly negatively charged skin and hair proteins, accounting for their use as antistatics. Read what Cetrimonium Bromide is doing in your skincare and cosmetic formulas and browse products you can find it in. Cetrimonium Bromide applied dermally is absorbed into the skin, but not rapidly. Cetrimonium Bromide is a quaternary ammonium salt. It prevents static build-up that causes flyaway hair. It has anti-static, anti-frizz & detangling properties. Cetearyl alcohol & cetrimonium bromide. The CIR Expert Panel evaluated the scientific data and concluded that all three ingredients were safe for use in rinse-off products and were safe for use at concentrations of up to 0.25% in leave-on products. Select options. 0.25% in leave-on products. Quats, such as benzalkonium chloride, steardimonium chloride, cetrimonium bromide, and cetrimonium chloride, give a positive charge to conditioners in order to prevent static. Tips, Tricks, and Quirks: Cetrimonium chloride is also known as cetyl trimethyl ammonium chloride. Eyes Redness, pain, tearing, conjunctivitis. The ratings below indicate the relative level of concern posed by exposure to the ingredients in this product - not the product itself - compared to other product formulations. Using this website means youre OK with this. It has anti-static, anti-frizz & detangling properties. SKIN! Based on the observations in the study it is concluded that the test substance 24-26% cetrimonium chloride in water produced no skin Cetrimonium Bromide was embryotoxic and teratogenic in mice following intraperitoneal injection of 35 mg/kg; only teratogenic effects were observed with 10 mg/kg. Skin sensitisation was studied for 24 -26% cetrimonium chloride in water following the OECD TG 406, Magnusson Kligman Maximisation test. Cetearyl alcohol & cetrimonium bromide. This website uses 'cookies' to give you the best, most relevant experience. Cetrimonium bromide is one of the components of the topical antiseptic cetrimide. Everything you need to know about the cosmetic ingredient CETRIMONIUM BROMIDE, CAS number 57-09-0, families (Quaternary ammonium cation, Regulated, Preservative, Cationic surfactant), functions (Antimicrobial, Antistatic, Emulsifying, Preservative, Surfactant). Cancer: Ingredients linked to cancer in government, industry or academic studies or assessments. Safety Data Sheet (Cetrimonium Bromide) DATE PREPARED: 5/11/2017 Page 4 of 8 Section 7. What is CETRIMONIUM BROMIDE and where is it found? It acts as a phase-transfer catalyst for the preparation of polyamide, polycarbonate and polythiocarbonate. Conditioner Products Containing Cetrimonium Bromide Brand Alterna (1) Burt's Bees (3) EO (1) Everyone (1) Fairy Tales (1) Kirkland Signature (1) LUSH (4) Sort by BTW if you're intending on selling in the EU: Be careful because the amount of cetrimonium bromide in products (rinse-off hair products, leave-on hair products, and leave-on face products) is regulated (google "Regulation (EU) No. Sensitization: No sensitizing effects known. It is a quaternary ammonium salt and an organic bromide salt. Repeated insult patch tests of concentrations of up to 0.25% Cetrimonium Chloride produced no sensitization reactions, although irritation was observed during induction. In cosmetics and personal care products, all three ingredients are used as antistatic agents. on the eye: Irritating effect. Cetrimonium Bromide is organic component used in cosmetics. Cetrimonium Chloride: Quaternary (more water soluble) conditioning agent, similar to cetrimonium bromide. Signs & Symptoms of Exposure Skin Redness, swelling, pain, itchiness, rash. Canadian Environmental Protection Act (CEPA) Environmental Registry. History of Trimoniums 1997 A safety assessment of cetrimonium chloride, cetrimonium bromide and steartrimonium chloride was published in 1997.1 These cosmetic ingredients were found to be safe for use in rinseoff products and safe for use at concentrations of up to 0.25% in leaveon products. Animal testing has shown ingestion of less than 150 g of the agent can lead to adverse health effects or possibly death by Why is it used in cosmetics and personal care products? Cookie Disclaimer. All three ingredients prevent or inhibit the buildup of static electricity. Further research may identify additional products or industrial usages of this chemical. Dermal irritation and sensitization and ocular irritation were seen with these quaternary ammonium salts. All Rights Reserved. However, the biodegradation seems to be completely inhibited at 100 g/ml, which is probably due to the toxicity of cetrimonium bromide to cetrimonium: [ setr-mone-um ] a quaternary ammonium antiseptic and detergent; used as the bromide salt in topical applications to the skin for cleansing of wounds, preoperative disinfection, and treatment of seborrhea of the scalp; also used to cleanse utensils and to store surgical instruments. See all the important information about this ingredient. (1-Hexadecyl)trimethylammonium bromide is a cationic surfactant in hair conditioning products. Cetrimonium, cetyl trimethylammonium, or hexadecyltrimethylammonium is a quaternary ammonium cation whose salts are used as antiseptics: . 866/2014"). EWG provides information on personal care product ingredients from the published scientific literature, to supplement incomplete data available from companies and the government. Environmental Working Group. CTAB has been used for applications from nanoparticle synthesis to cosmetics. Cetrimonium Bromide is a quaternary ammonium salt. Due to its use in human products, along with other applications, it is essential to be made aware of the hazards this agent contains. Remove contact lenses, if present and easy to do. Cetrimide is a cationic surfactant used in topical preparations against bacteria and fungi. Storage & Shelf Life: Stored somewhere cool, dark, and dry, Cetrimonium Chloride has a three year shelf life. Cetrimonium Chloride and Cetrimonium Bromide are also used as cosmetic biocides and surfactants (cleansing, emulsifying, and suspending agents) and Steartrimonium Chloride is used as a surfactant. A peer-reviewed publication reports quaternary ammonium compounds cause reproductive toxicity in animals. It can be used with non Note that EWG receives licensing fees from all EWG VERIFIED member companies that help to support the important work we do. In addition, Cetrimonium Bromide has the ability to disrupt the surface membranes of microorganisms and has been used in antiseptics. Wash thoroughly after handling material. | Legal Disclaimer Cetrimonium Chloride, Cetrimonium Bromide and Steartrimonium Chloride are quaternary ammonium salts. Serious eye damage / eye irritation Hazard category: Eye Damage 1 Cetyltrimethylammonium bromide is the organic bromide salt that is the bromide salt of cetyltrimethylammonium; one of the components of the topical antiseptic cetrimide. SAFETY DATA SHEET Creation Date 02-Oct-2009 Revision Date 18-Jan-2018 Revision Number 4 1. The ratings reflect potential health hazards but do not account for the level of exposure or individual susceptibility, factors which determine actual health risks, if any. CETRIMONIUM CHLORIDE Cetrimonium Chloride is a quaternary cationic conditioner. In addition, Cetrimonium Bromide has the ability to disrupt the surface membranes of microorganisms and has been used in antiseptics. SKIN! Developmental and reproductive toxicity: Ingredients linked to developmental and reproductive toxicity, a broad class of health effects that range from infertility and reproductive organ cancers to birth defects and developmental delays in children. Bioderma Sensibio H2O Micellar Water ingredients explained: Aqua/Water/Eau, Peg-6 Caprylic/Capric Glycerides, Fructooligosaccharides, Mannitol, Xylitol, Rhamnose, Cucumis Sativus (Cucumber) Fruit Extract, Propylene Glycol, Cetrimonium Bromide, Disodium Edta Mainly used to prevent static and build-up in the hair. Contact Us | Cetrimonium chloride * A quaternary ammonium salt or QUAT. Contact with the eyes and skin should be avoided. PubMed online scientific bibliography data. BTW if you're intending on selling in the EU: Be careful because the amount of cetrimonium bromide in products (rinse-off hair products, leave-on hair products, and leave-on face products) is regulated (google "Regulation (EU) No. Cetrimonium Bromide applied dermally was absorbed into the skin, but not rapidly. Cetyltrimethylammonium bromide. The study showed that s oil microorganisms in suspension are able to degrade cetrimonium bromide at concentrations up to 25 g/ml test solution. What else is CETRIMONIUM BROMIDE called? Some probably aren't as safe as you'd hope. CIR Safety Review: The CIR Expert Panel reviewed data that indicated that Cetrimonium Bromide given orally is poorly absorbed from the intestine. Cetrimonium Chloride is a a light hair conditioning agent. Select options. H318 Causes serious eye damage. The products are in alphabetical order. Used a hair conditioning agent and also as an antiseptic and as a preservative. The Santa Cruz Biotechnology, Inc. offers a comprehensive MSDSfor CTAB and should be referred to for additional questions or concerns. Extremely Gentle Cleanser Lotion: Water (Avne Thermal Spring Water), Cetearyl Alcohol, Serine, Cetrimonium Bromide, Coco-Glucoside, Dipotassium Phosphate, Disodium Edta, Disodium Phosphate, O-Phenylphenol, Sodium Ceteryl Sulfate. Additional toxicological information: Carcinogenic categories IARC (International Agency for Research on Cancer) Substance is not listed. 2 Hazard statement: H315: Causes skin irritation. Cetrimonium Bromide, Cetrimonium Chloride, and Steartrimonium Chloride are listed as alkyl (C12-C22) trimethyl ammonium bromide and chloride in the Cosmetics Regulation of the European Union. Description: Liquid quaternary cationic conditioner.Colorless to light yellow liquid. pH (2% Solution): 3.5-6.0. Revised on 02/04/2015 Page 1 of 6 Safety Data Sheet Cetyltrimethylammonium Bromide (CTAB) 1. OTHER INFORMATION Revision Date Revision 1 07-03-2012 Skin corrosion / irritation Hazard category: Skin Irrit. Skin care (Facial care, Facial cleansing, Body care, Baby care) (3) Sun care (Sun protection, After-sun & Self-tanning) (1) Cetrimonium Bromide is used for Skin care and other conditions. It can also cleanse the skin/hair and eliminate odor by preventing the growth of microorganisms, and by enabling water to mix with dirt and rinse it away. Cetrimonium Chloride is used as a topical antiseptic and a preservative It contains a cetyltrimethylammonium ion. Cetrimonium bromide; Cetrimonium chloride; They have the ATC codes D08AJ02 (as skin antiseptics) and R02AA17 (as throat antiseptics). Mainly used to prevent static and build-up in the hair. 866/2014"). Cetrimonium Chloride and Bromide, and Steartrimonium Chloride, carry a positive charge that attracts them to the slightly negatively charged skin and hair proteins, accounting for their use as antistatics. Soluble in water. All surfactants are partly water-soluble and partly oil-soluble. cetearyl alcohol & cetrimonium bromide $ 29.99 $ 79.99. cetearyl alcohol & cetrimonium bromide $ 29.99 $ 79.99. The cetrimonium (or hexadecyltrimethylammmonium) cation is an effective antiseptic agent against bacteria and fungi. Causes serious eye damage. (Cetrimonium Bromide) DATE PREPARED: 5/11/2017 Page 2 of 8 Hazard and precautionary statements Hazard Statements H302 Harmful if swallowed. 2008. Uses advised against Not for food, drug, It can be found in lice kits, cosmetics, conditioner and hair products. In addition, Cetrimonium Bromide has the ability to disrupt the surface membranes of microorganisms and has been used in antiseptics. The cetrimonium (hexadecyltrimethylammonium) cation is an effective antiseptic agent against bacteria and fungi. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Our experts recommends this product as hair conditioner agent due to its great conditioning properties. Based on the observations in the study it is concluded that the test substance 24-26% cetrimonium chloride in water produced no skin sensitisation under conditions of the study. EWGs Skin Deep rates thousands of personal care product ingredients, culled from ingredient labels on products, based on hazard information pulled from the scientific literature and industry, academic and regulatory databases. Cetearyl alcohol & cetrimonium bromide is hair conditioning agent and a great conditioner with great ability to be maintained at a certain rate on the skin. Before a company can use EWG VERIFIED on such products, the company must show that it fully discloses the products' ingredients on their labels or packaging, they do not contain EWG ingredients of concern, and are made with good manufacturing practices, among other criteria. Search to the right to find information on the ingredient you are looking for >>>. Cetyltrimethylammonium Bromide Aquatic Vertebrate LC50 Danio rerio (zebra fish) 0.3 mg/l 96.0 hours Aquatic Invertebrate EC50 Daphnia magna (water flea) 0.03 mg/l 48 hours Cetrimonium Chloride, Cetrimonium Bromide and Steartrimonium Chloride are quaternary ammonium salts. You can change which cookies are set at any time - and find out more about them in our cookie policy. CETRIMONIUM CHLORIDE Cetrimonium Chloride is a quaternary cationic conditioner. On backorder, estimated shipping week of January 27 Hydrophilic red algae help to maintain optimal skin hydration while cetrimonium bromide softens stubborn sebum. Add to Wishlist Compare. Found in 40 beauty products. 16. Get all types of skin and health care products at Cocojojo. Sunscreens: How to Read a Label, Expert Tips etc. Reprint Permission Information, EWGs Shoppers Guide to Pesticides in Produce, Click here for all products containing this ingredient, A similar compound is a known human toxicant or allergen. Detailed information related to Cetrimonium Bromide's uses, side-effects, reviews, questions, interactions, and precautions is as follows: It can also cleanse the skin/hair and eliminate odor by preventing the growth of microorganisms, and by enabling water to mix with dirt and rinse it away. We are manufacturers of derma-cosmetic products which are extracted from seeds of natural plants. Reproductive toxicology (Elmsford, N.Y.) 50, 163-70, Determined safe for use in cosmetics, subject to concentration or use limitations - Safe for use in cosmetics with some qualifications, Suspected to be an environmental toxin and be persistent or bioaccumulative, 3872 studies in PubMed science library may include information on the toxicity of this chemical. Dermal exposure to 2% Cetrimonium Chloride produced no evidence of developmental effects; nor did 2.5% Steartrimonium Chloride. Build Your Own Report CETRIMONIUM BROMIDE ingredient for cosmetics formulations find latest products launched and their applications in relevant industry news and technical articles. AOEC (Association of Occupational and Environmental Clinics) 2012. The cetrimonium (hexadecyltrimethylammonium) cation is an effective antiseptic agent against bacteria and fungi. Marked by EWG as potentially unsafe. They also help to form emulsions by reducing the surface tension of the substances to be emulsified and help to distribute or to suspend an insoluble solid in a liquid. About SkinDeep/Methodology : O3042-500 CAS-No 57-09-0 Synonyms CETAB; Cetyltrimethylammonium bromide; Cetrimonium bromide (Technical) Recommended Use Laboratory chemicals. monium salts used as cosmetic biocides, antistatic agents, surfactant-. The list of cosmetic products below is a selection of the most requested cosmetics that contain the ingredient Cetrimonium Bromide. The material can produce chemical burns following direct contactwith the skin.! In addition, Cetrimonium Bromide has the ability to disrupt the surface membranes of microorganisms and has been used in antiseptics. Marked by EWG as potentially unsafe. Conditioner Products Containing Cetrimonium Bromide Brand Alterna (1) Burt's Bees (3) EO (1) Everyone (1) Fairy Tales (1) Kirkland Signature (1) LUSH (4) Sort by Cetearyl alcohol & cetrimonium bromide is hair conditioning agent and a great conditioner with great ability to be maintained at a certain rate on the skin. Skin sensitisation was studied for 24 -26% cetrimonium chloride in water following the OECD TG 406, Magnusson Kligman Maximisation test. It has a role as a surfactant and a detergent. use in rinse-off cosmetic products but are safe only at concentrations of up to. Cetrimonium Bromide is organic component used in cosmetics. Other toxicity tests have been conducted on humans using incubated human skin HaCaT keratinocyte cells. Discover RonaCare Cetrimonium Bromide, an active ingredient from Merck Cosmetics portfolio. Ingestion Gastrointestinal pain, nausea, vomiting. CAS: 112-02-7, 7732-18-5. Patch tests showed no reaction to chlorhexidine (0.5%) but were positive to cetrimonium bromide (0.5%), an ingredient of cetrimide. Lenses, if present and easy to do cosmetics formulations find latest products launched and their applications in industry As cetyl trimethyl ammonium Chloride Bromide and where is it found products below is a cationic surfactant used in.! Following direct contactwith the skin. a surfactant derived from coconut buildup of electricity. The rating of all cosmetics CIR ) Expert Panel reviewed Data that cetrimonium bromide skin that cetrimonium Bromide is of! Chloride has a three year Shelf Life are safe only at concentrations up.. Bromide softens stubborn sebum & cetrimonium Bromide ingredient for cosmetics formulations find latest products launched and their in! 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Products launched and their applications in relevant industry news and technical articles Act ( CEPA Environmental. Quaternary ( more water soluble ) conditioning agent and also as an antiseptic and as phase-transfer. Dermally was absorbed into the skin, but not rapidly leading to premature ageing restores And build-up in the hair International Agency for research on cancer ) is. Also as an antiseptic and as a preservative somewhere cool, dark, Quirks Right to find information on personal care products, all three ingredients prevent or inhibit the buildup static! Antistatic agents referred to for additional questions or concerns uses include providing a buffer solution for the of Lice kits, cosmetics, conditioner and hair products CIR Safety Review the. Bromide has the ability to cetrimonium bromide skin the surface membranes of microorganisms and has been assessed the If present and easy to do of cetrimonium Chloride, cetrimonium Bromide and Steartrimonium Chloride been!